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CAS NO.26016-98-8
Fosfomycin Calcium
Assay: 95.0%~101.0%
Certification: GMP
Standard: EP7.0
Fosfomycin is indicated in the treatment of urinary tract infections, where it is usually administered as a single
oral megadose. Its use in combination with tobramycin to treat lung infections in patients withcystic fibrosis
wasalso explored. The drug is well tolerated and has a low incidence of harmful side-effects.
Fosfomycin has broad antibacterial activity against both Gram-positive and Gram-negative pathogens, with very useful activity against E. faecails, E. coil, and various Gram-negative like Cirtobacter and Proteus.Givenactivity in a low pH milieu, and predominant excretion in activity from into the urine, fosfomycin was found
use for the prophylaxis and treatment of urinary tract infectious caused by these uropathogens.
Specifications of Fosfomycin Calcium:
|
Items |
Specifications |
Results |
|
Characters |
White or almost white powder |
Complies |
|
Reaction of calcium |
It gives reaction (a) of calcium |
Positive |
|
pH |
8.1-9.6 |
8.7 |
|
Chlorides |
≤0.2% |
<0.2% |
|
Heavy metals |
≤20ppm |
<20ppm |
|
Water |
8.5%~11.5% |
9.2% |
|
Assay |
95.0%~101.0% |
99.3% |