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Shandong Jiulong Hisince Pharmaceutical Co.,Ltd.

Country: China (Mainland)

Business Type:Manufacturers

Mr.Richard Bai

Tel: +86-15853188990

Ms.Betty Xue

Tel: +86-13255689879

Ms.Sindy Zhang

Tel: +86-13706449112

Mr.Richard

Tel: 0531-69953158

Ms.Essence Sun

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Province/state: Shandong

City: Jinan

Street: Huadian Pioneer Park, Huadian Township, Qihe County, Dezhou City, Shandong, P.R.China

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amisulpride 71675-85-9

CAS NO.71675-85-9

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/P,T/T
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Product Details

Keywords

  • Amisulpride
  • Amisulpride with high quality
  • 71675-85-9

Quick Details

  • ProName: amisulpride 71675-85-9
  • CasNo: 71675-85-9
  • Appearance: whilt powder
  • Application: API
  • DeliveryTime: prompt
  • PackAge: durm
  • Port: shanghai
  • ProductionCapacity: 1000 Kilogram/Day
  • Purity: 99.5%
  • Storage: cool and dryer
  • Transportation: by sea or by air
  • LimitNum: 1 Kilogram
  • Valid Period: 2 years

Superiority

【Biological Activity]

Potent, selective dopamine D 2 and D 3 receptor antagonist. K i values are 2.8 and 3.2 nM respectively for human D 2 and D 3 and > 1000 nM for human D 1 , D 4 and D 5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D 2 /D 3 receptors at higher doses. Preferentially interacts with limbic D 2 -like receptors in vivo . Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride.

【Therapeutic Uses]

Neuroleptic agent, an analogue of sulpiride. Used as an antipsychotic. Dopamine receptor antagonist

【Biomedical Effects and Toxicity]

Potent, selective dopamine D 2 and D 3 receptor antagonist. K i values are 2.8 and 3.2 nM respectively for human D 2 and D 3 and > 1000 nM for human D 1 , D 4 and D 5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D 2 /D 3 receptors at higher doses. Preferentially interacts with limbic D 2 -like receptors in vivo . Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride.

Details

Chemical and Physical Properties

【Appearance】
White or almost white crystalline powder
【Density】
1.2 g/cm3
【Melting Point】
124-128oC
【Boiling Point】
558.9 °C at 760 mmHg
【Refractive Index】
1.545
【Flash Point】
291.8 °C
【Water】
Soluble to 50 mM in 1eq. HCl and to 50 mM in DMSO
【Solubilities】
Soluble to 50 mM in 1eq. HCl and to 50 mM in DMSO
【Color/Form】
white
【Storage temp】
2-8°C

Safety and Handling

【Hazard Codes】
Xn:Harmful
【Risk Statements】
R22
【Safety Statements 】
S22;S24/25
【Safety】

Hazard Codesof Amisulpride (CAS NO.71675-85-9):HarmfulXn
Risk Statements: 22
R22: Harmful if swallowed.
Safety Statements: 22-24/25
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: CV2308701

【Specification】

Off-White Solid
usageEng:Neuroleptic agent, an analogue of sulpiride. Used as an antipsychotic. Dopamine receptor antagonist
Safety Statements:22-24/25
22:Do not breathe dust
24/25:Avoid contact with skin and eyes

Use and Manufacturing

【Usage】

Neuroleptic agent, an analogue of sulpiride. Used as an antipsychotic. Dopamine receptor antagonist

 

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